Risk Factors for Long-term Outcomes after Initial Treatment in Hepatolithiasis

Title
Risk Factors for Long-term Outcomes after Initial Treatment in Hepatolithiasis
Authors
박신구
Keywords
Cholelithiasis; Bile Ducts; Intrahepatic; Risk Factors; Complication
Issue Date
2013
Publisher
JOURNAL OF KOREAN MEDICAL SCIENCE
Series/Report no.
JOURNAL OF KOREAN MEDICAL SCIENCE ; 제28권 제11호 pp 1627~1631
Abstract
Hepatobiliary complications, such as stone recurrence, recurrent cholangitis, liver abscess, secondary biliary cirrhosis, and cholangiocarcinoma may occur after treatment for hepatolithiasis. However, few previous studies have addressed the risk factors and longterm outcomes after initial treatment. Eighty-five patients with newly diagnosed hepatolithiasis, actively treated for hepatolithiasis, constituted the cohort of this retrospective study. Patients were treated by hepatectomy or nonoperative percutaneous transhepatic cholangioscopic lithotomy. Long-term complications, such as recurrent cholangitis, liver abscess, secondary biliary cirrhosis, and cholangiocarcinoma, and their relationships with clinical parameters were analyzed. The mean follow-up period was 57.4 months. The overall hepatobiliary complication rate after the treatment was 17.6%. Multivariate analysis of suspected risk factors showed that complications were associated with age (HR, 1.046; CI, 1.006-1.089), bile duct stricture (HR, 4.894; CI, 1.295-18.495), and residual stones (HR, 3.482; CI, 1.214-9.981). In conclusion, several long-term hepatobiliary complications occur after hepatolithiasis treatment, and regular observation is necessary in patients with concomitant biliary stricture or residual stones.
URI
http://dx.doi.org/10.3346/
http://dspace.inha.ac.kr/handle/10505/33846
ISSN
1011-8934
Appears in Collections:
Medical School/College of Medicine (의학전문대학원/의과대학) > Medical Science (의학) > Local Access Journal Papers, Reports(의학 논문, 보고서)

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