The effects of aerobic treadmill exercise training on insulin resistance and bone metabolic turnover in diabtes mellitus rats

Title
The effects of aerobic treadmill exercise training on insulin resistance and bone metabolic turnover in diabtes mellitus rats
Authors
박동호
Keywords
aerobic treadmill exercise, insulin resistance, bone metabolic turnover, bone mineral density, diabetes mellitus, rats
Issue Date
2013
Publisher
Journal of Exercise Nutrition & Biochemistry
Series/Report no.
Journal of Exercise Nutrition & Biochemistry; 제17권 제 3호 pp 61~69
Abstract
The purpose of this study is to verify the effect of exercise on bone mass reduction generated by diabetes mellitus (DM) by imposing an 8-week aerobic treadmill exercise to DM-induced rat model and reviewing DM related factors and bone metabolic markers. This study involved thirty 7-week-old, male Sprague-Dawley (SD) rats and divided them into three groups of control (C, n = 10), DM (DC, n = 10), and DM+exercise (DE, n = 10) comprising ten rats each. Diabetes mellitus in the DM group was induced by streptozotocin (STZ). Aerobic exercise was implemented 30 min a day, 5 times a week for 8 weeks. Average exercise intensity was 10m/min from the 1st to the 4th week, and 12m/min from the 5th to the 8th week on 0 percent slope. Consequently, the body weight of rats decreased significantly due to induced DM (p < .001), and showed a significantly increasing tendency after performing exercise (p < .001). Serum insulin level showed a slightly increasing trend as DM developed (N.S.), and showed a
URI
http://dx.doi.org/10.5717/jenb.2013.17.3.61
http://dspace.inha.ac.kr/handle/10505/33774
ISSN
2233-6834
Appears in Collections:
School of Arts & Sports(예술체육학부) > Kinesiology (스포츠과학) > Local Access Journal Papers (스포츠과학_학술논문)

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