Passive contact guidance of fibroblast cells using consecutive trapezoidal micropatterns

Title
Passive contact guidance of fibroblast cells using consecutive trapezoidal micropatterns
Authors
윤상희
Issue Date
2013
Publisher
APPLIED PHYSICS LETTERS
Series/Report no.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY; vol.102 no.13 startpage 1/133701 endpage 5/133701
Abstract
Cell migration on micropatterned substrates is a complex process regulated by cell-substrate interactions. This paper presents a passive method for guiding the migration of NIH 3T3 fibroblasts using consecutive trapezoidal micropatterns, made of a biocompatible photopolymer (OrmoCompVR ), to provide tapered micro-features on the cells. The cell migration paths measured from our platforms quantitatively address the dependence of the migratory behavior of the cells on the tapered micro-features. Most of the cells on the micropatterns have moved in a converging direction rather than in a diverging one; migration speed on the micropatterns has been noticeably faster than that on flat substrates
URI
http://dx.doi.org/10.1063/1.4799169
http://dspace.inha.ac.kr/handle/10505/31606
ISSN
0003-6951
Appears in Collections:
College of Engineering(공과대학) > Mechanical Engineering(기계공학) > Journal Papers, Reports(기계공학 논문, 보고서)
Files in This Item:
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