A Single Amino Acid Substitution Alters Substrate Specificity of the Yeast Protein Tyrosine Phosphatase YPTP1

Title
A Single Amino Acid Substitution Alters Substrate Specificity of the Yeast Protein Tyrosine Phosphatase YPTP1
Authors
Cho, H.
Keywords
ESCHERICHIA-COLI, PEPTIDES
Issue Date
1999-10
Publisher
KOREAN CHEMICAL SOC
Abstract
Protein tyrosine phosphatases (PTPases) constitute a family
of enzymes that catalyze the hydrolysis of a phosphate
moiety from a phosphotyrosyl residue of a protein.1~5 Because
of the biological importance of the reversible tyrosine phosphorylation,
much research has been focused on the PTPases
since its first identification in 1988.6 More than 70 PTPases
have been identified in various organisms including human
to yeasts.7 Much progress has been achieved in the study of
the mechanism of catalysis.4
URI
http://dspace.inha.ac.kr/handle/10505/20362
ISSN
0253-2964
Appears in Collections:
College of Natural Science(자연과학대학) > Chemistry (화학) > Journal Papers, Reports(화학 논문, 보고서)
Files in This Item:
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