Estimation for Retention Factor of Isoflavones in Physico-Chemical Properties

Title
Estimation for Retention Factor of Isoflavones in Physico-Chemical Properties
Authors
Row, K.H.
Keywords
physico-chemical properties, retention factors
Issue Date
2003-09
Publisher
KOREAN CHEMICAL SOC
Abstract
The estimation of retention factors by correlation equations with physico-chmical properties maybe helpful in chromatographic work. The physico-chemical properties were water solubility (S), hydrophobicity (P), total energy (E-t), connectivity index 1 (X-1), hydrophilic-lipophlic balance (x) and hydrophilic surface area (h) of isoflavones. The retention factors were experimentally measured by RP-HPLC. Especially, the empirical regulations of water solubility and hydrophobicity were expressed in a linear form. The equation between retention factors and various physico-chemical properties of isoflavones was suggested as k = a(0) + a(1)log S + a(2)log P-Q + a(3) (E-t) + a(4) (X-1) + a(5) (x) + a(6) (h), and the correlation coefficients estimated were relatively higher than 0.95. The empirical equations might be successfully used for a prediction of the various chromatographic characteristics of substances, with a similar chemical structure.
URI
http://dspace.inha.ac.kr/handle/10505/20316
ISSN
0253-2964
Appears in Collections:
College of Engineering(공과대학) > Chemical Engineering (화학공학) > Journal Papers, Report (화학공학 논문, 보고서)
Files in This Item:
Estimation.pdfDownload

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse