The Causative Organisms of Bacterial Meningitis in Korean Children in 1996-2005

Title
The Causative Organisms of Bacterial Meningitis in Korean Children in 1996-2005
Authors
Cho, H.K.; Lee, H.; Kang, J.H.; Kim, K.N.; Kim, D.S.; Kim, Y.K.; Kim, J.S.; Kim, J.H.; Kim, C.H.; Kim, H.M.; Park, S.E.; Oh, S.H.; Chung, E.H.; Cha, S.H.; Choi, Y.Y.; Hur, J.K.; Hong, Y.J.; Lee, H.J.; Kim, K.H.
Keywords
Meningitis, Bacterial, Streptococcus pneumoniae
Issue Date
2010-06
Publisher
KOREAN ACAD MEDICAL SCIENCES
Abstract
Bacterial meningitis remains a serious cause of morbidity and mortality in childhood, despite the availability of effective vaccines against Haemophilus influenzae type b (Hib) or Streptococcus pneumoniae. The purpose of this study was to analyze data on bacterial meningitis cases in Korea from 1996 through 2005. The information of all hospitalized bacteria-proven meningitis cases was obtained from 17 university hospitals nationwide. A total of 402 cases were identified. Of these, 125 (29.9%) cases were neonates. Streptococcus agalactiae was the most common bacteria responsible for 99 (24.6%) of all cases regardless of age, followed by S. pneumoniae for 91 (22.6%) and H. influenzae for 67 (16.7%) patients. The common etiology beyond the neonatal period was S. pneumoniae for 91 (33.0%) followed by H. influenzae for 63 (22.8%) patients. The overall case fatality rate was 9.4%, which was similar with that in 1986-1995. In conclusion, S. agalactiae, S. pneumoniae and H. influenzae were important etiologic agents of bacterial meningitis in children in the last 10 yrs. It is required to establish the preventive strategy of the three bacteria. The nationwide epidemiologic study should be continued to evaluate immunization strategy and efficacy.
URI
http://dspace.inha.ac.kr/handle/10505/20138
ISSN
1011-8934
Appears in Collections:
Medical School/College of Medicine (의학전문대학원/의과대학) > Medical Science (의학) > Journal Papers, Reports(의학 논문, 보고서)
Files in This Item:
the.pdfDownload

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse