Rational Strain Improvement for a Doxorubicin-overproducing Streptomyces Industrial Mutant via Genetic Manipulation of wblA Ortholog and wblA-dependent SCO4967

Title
Rational Strain Improvement for a Doxorubicin-overproducing Streptomyces Industrial Mutant via Genetic Manipulation of wblA Ortholog and wblA-dependent SCO4967
Authors
노준희
Keywords
rationalstrainimprovementforadoxorubicinoverproducingstreptomycesindustrialmutantviageneticmanipulationofwblaorthologandwbladependentsco4967
Issue Date
2010
Publisher
인하대학교
Abstract
Cross-genome comparative transcriptome analyses were previously conducted using the sequenced Streptomyces coelicolor genome microarrays to understand the genetic nature of doxorubicin (DXR) and daunorubicin (DNR) overproducing industrial mutant (OIM) of
Description
1. Introduction 1 2. Materials and Methods 5 2.1 Bacterial strains, plasmids and condition 5 2.2 Cloning and sequence analysis of wblA ortholog from S. peucetius OIM genomic library 5 2.3 Inactivation of wblAspe in S. peucetius OIM strain 6 2.4 High
URI
http://dspace.inha.ac.kr/handle/10505/15718
Appears in Collections:
College of Natural Science(자연과학대학) > Ocean Sciences (해양과학) > Theses(해양과학 석박사 학위논문)
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