Acute geometric changes of the mitral annulus after coronary occlusion: A real-time 3D echocardiographic study

Title
Acute geometric changes of the mitral annulus after coronary occlusion: A real-time 3D echocardiographic study
Authors
Kwan, J.
Keywords
mitral valve, mitral annulus, echocardiography
Issue Date
2006-04
Publisher
KOREAN ACAD MEDICAL SCIENCES
Abstract
We performed real-time 3D echocardiography in sixteen sheep to compare acute geometric changes in the mitral annulus after left anterior descending coronary artery (LAD, n=8) ligation and those after left circumflex coronary artery (LCX, n=8) ligation. The mitral regurgitation (MR) was quantified by regurgitant volume (RV) using the proximal isovelocity surface area method. The mitral annulus was reconstructed through the hinge points of the annulus traced on 9 rotational apical planes (angle increment=20 degrees). Mitral annular area (MAA) and the ratio of antero-posterior (AP) to commissure-commissure (CC) dimension of the annulus were calculated. Non-planar angle (NPA) representing non-planarity of the annulus was measured. After LCX occlusion, there were significant increases of the MAA during both early and late systole (p < 0.01) with significant MR (RV: 30 +/- 14 mL), while there was neither a significant increase of MAA, nor a significant MR (RV: 4 5 mL) after LAD occlusion. AP/CC ratio (p < 0.01) and NPA (p < 0.01) also significantly increased after LCX occlusion during both early and late systole. The mitral annulus was significantly enlarged in the antero-posterior direction with significant decrease of non-planarity compared to LAD occlusion immediately after LCX occlusion.
URI
http://dspace.inha.ac.kr/handle/10505/1864
ISSN
1011-8934
Appears in Collections:
Medical School/College of Medicine (의학전문대학원/의과대학) > Medical Science (의학) > Journal Papers, Reports(의학 논문, 보고서)
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